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KMID : 0615720160330010079
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Jouranl of Korean Acupuncture and Moxibustion society
2016 Volume.33 No. 1 p.79 ~ p.93
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A Review of Research Trends in Gold Implantation Therapy Focused on Gold Thread, Gold Needle and Gold Bead
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Jo Dae-Hyun
Baatarkhuyag Ariunchimeg
Jo Ye-Eun
Lee Sang-Hoon
Lee Jae-Dong
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Abstract
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Objectives: The purpose of this study is to explore research trends in gold implantation therapy performed on the animal and human body, through a review of clinical studies focused on gold thread, gold needle and gold bead.
Methods: Medical databases, including Pubmed, CENTRAL, MEDLINE, EMBASE, RISS4u, KISTI, OASIS and KTKP, were searched for relevant articles published from their launch to December 31, 2015 using the key word ‘gold’ with ‘thread*’, ‘needle*’, ‘acupuncture*’, ‘wire*’, ‘bead*’, ‘embed*’, ‘ implant*’, or ‘insert*’. The results were classified into in vivo studies, clinical trials and clinical reports. Analysis of the results was conducted in several research areas, from the identity of studies such as nationality and published year, to the gold preparations-features and implanted locations and to the outcomes that reflect the clinically favorable or adverse effect of gold implantation therapy.
Results: A total of 30 studies including 11 in vivo studies, 4 clinical trials and 15 case reports, were found in the search. We observed certain research trends according to the research time, nationality and target indication of the studies. The studies primarily revealed a chronic local inflammatory response which could be a useful mechanism for pain-relief in musculoskeletal diseases and facial rejuvenation. Researches concerning long-term reactions or adverse effects were rare.
Conclusion: The results show that the efforts to discover the level of clinical efficacy of gold implantation therapy were steady and worldwide. However, further researches on the longterm effect, and more importantly, the safety of gold implantation therapy are required.
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KEYWORD
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Gold thread , Gold needle , Gold bead , Research trend , Efficacy , Safety
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